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• Activity deltas table
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Motif ID: SOX{8,9,10}.p2

Z-value: 0.875

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_8815266	8.456		MFAP5	microfibrillar associated protein 5
chr12_-_8815370	6.762	NM_003480	MFAP5	microfibrillar associated protein 5
chr7_-_83270746	5.556	NM_001178129	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr16_+_82660573	5.356		CDH13	cadherin 13, H-cadherin (heart)
chr16_+_82660641	4.865		CDH13	cadherin 13, H-cadherin (heart)
chr12_-_45270071	4.740		NELL2	NEL-like 2 (chicken)
chr16_+_82660390	4.673	NM_001220488 NM_001220489 NM_001220490 NM_001220491 NM_001220492 NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr8_-_82395401	4.118	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr16_+_69141442	4.010	NM_005329	HAS3	hyaluronan synthase 3
chr19_-_51568323	3.757	NM_015596	KLK13	kallikrein-related peptidase 13
chrX_-_38079980	3.686	NM_001170750 NM_001170751 NM_001170752 NM_006307	SRPX	sushi-repeat containing protein, X-linked
chr19_+_36359346	3.622	NM_001024807 NM_005166	APLP1	amyloid beta (A4) precursor-like protein 1
chr12_-_45270157	3.611	NM_001145108 NM_006159	NELL2	NEL-like 2 (chicken)
chrX_+_84498993	3.556	NM_021998	ZNF711	zinc finger protein 711
chr3_+_186648515	3.447		ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr17_-_16472463	3.333	NM_020653	ZNF287	zinc finger protein 287
chr5_-_146435589	3.324	NM_181674 NM_181676	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr2_+_217498082	3.190	NM_000597	IGFBP2	insulin-like growth factor binding protein 2, 36kDa
chr8_-_20112691	3.076	NM_021020	LZTS1	leucine zipper, putative tumor suppressor 1
chr12_-_8815479	3.043		MFAP5	microfibrillar associated protein 5
chr1_+_45792544	3.036	NM_032756	HPDL	4-hydroxyphenylpyruvate dioxygenase-like
chrX_-_64196268	2.852	NM_001178033 NM_018684	ZC4H2	zinc finger, C4H2 domain containing
chrX_+_84499037	2.839		ZNF711	zinc finger protein 711
chr11_-_16424391	2.777	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr17_-_39728304	2.673	NM_000226	KRT9	keratin 9
chr12_-_45269953	2.570		NELL2	NEL-like 2 (chicken)
chr15_-_42186274	2.464	NM_016642	SPTBN5	spectrin, beta, non-erythrocytic 5
chr1_+_153003677	2.405	NM_003125	SPRR1B	small proline-rich protein 1B
chr9_+_4792876	2.381		RCL1	RNA terminal phosphate cyclase-like 1
chr9_+_4792974	2.380		RCL1	RNA terminal phosphate cyclase-like 1
chr17_+_67498391	2.317		MAP2K6	mitogen-activated protein kinase kinase 6
chr7_+_28452143	2.239	NM_182898	CREB5	cAMP responsive element binding protein 5
chr17_-_46655544	2.238	NM_024015	HOXB4	homeobox B4
chr1_-_153363544	2.238	NM_002964	S100A8	S100 calcium binding protein A8
chr2_-_127977653	2.232		CYP27C1	cytochrome P450, family 27, subfamily C, polypeptide 1
chr5_+_140602914	2.220	NM_018934	PCDHB14	protocadherin beta 14
chr17_-_39743085	2.171	NM_000526	KRT14	keratin 14
chr7_+_80267782	2.137	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr8_+_126442557	2.097	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr1_-_221915393	2.095		DUSP10	dual specificity phosphatase 10
chr6_+_21666645	2.088		LINC00340	long intergenic non-protein coding RNA 340
chr7_+_69064316	2.084		AUTS2	autism susceptibility candidate 2
chr9_+_4792833	1.996	NM_005772	RCL1	RNA terminal phosphate cyclase-like 1
chr12_-_62997207	1.973	NM_175895	C12orf61	chromosome 12 open reading frame 61
chr8_-_29206321	1.956	NM_057158	DUSP4	dual specificity phosphatase 4
chr20_+_44746948	1.925		CD40	CD40 molecule, TNF receptor superfamily member 5
chr1_-_221915458	1.881	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr10_+_6244839	1.877	NM_004566	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_+_35225341	1.856	NM_153212	GJB4	gap junction protein, beta 4, 30.3kDa
chr5_+_140593508	1.845	NM_018933	PCDHB13	protocadherin beta 13
chr12_+_113495661	1.836	NM_004416	DTX1	deltex homolog 1 (Drosophila)
chrX_+_65384078	1.833	NM_001130860 NM_014799	HEPH	hephaestin
chr5_-_16936371	1.815	NM_012334	MYO10	myosin X
chr9_+_2622134	1.800		VLDLR	very low density lipoprotein receptor
chr12_+_70759974	1.788	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr14_+_77228940	1.778		VASH1	vasohibin 1
chr2_-_208031570	1.777		KLF7	Kruppel-like factor 7 (ubiquitous)
chr9_+_112403067	1.772	NM_001037293	PALM2	paralemmin 2
chr3_-_185826748	1.759	NM_004454	ETV5	ets variant 5
chrX_+_107288199	1.756	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr7_+_142560512	1.750		EPHB6	EPH receptor B6
chr5_-_16936290	1.745		MYO10	myosin X
chr12_-_10282680	1.742	NM_022570 NM_197947 NM_197948 NM_197949 NM_197950 NM_197954	CLEC7A	C-type lectin domain family 7, member A
chr1_-_221915426	1.726		DUSP10	dual specificity phosphatase 10
chr11_-_67141647	1.718	NM_001166212	CLCF1	cardiotrophin-like cytokine factor 1
chr9_+_2622099	1.667		VLDLR	very low density lipoprotein receptor
chr8_-_21988518	1.656	NM_005144 NM_018411	HR	hairless homolog (mouse)
chr8_+_82192717	1.651	NM_001444	FABP5	fatty acid binding protein 5 (psoriasis-associated)
chr8_-_103667882	1.612	NM_005655	KLF10	Kruppel-like factor 10
chr1_-_16539103	1.575	NM_153213	ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19
chr3_-_50649080	1.554		CISH	cytokine inducible SH2-containing protein
chr17_-_37764165	1.553	NM_006160	NEUROD2	neurogenic differentiation 2
chr20_-_56285576	1.551	NM_199169 NM_199170	PMEPA1	prostate transmembrane protein, androgen induced 1
chr2_+_166428845	1.544	NM_024969	CSRNP3	cysteine-serine-rich nuclear protein 3
chr11_+_111808017	1.539		DIXDC1	DIX domain containing 1
chr17_+_54230835	1.534	NM_153228	ANKFN1	ankyrin-repeat and fibronectin type III domain containing 1
chr3_-_193272587	1.523	NM_032279	ATP13A4	ATPase type 13A4
chr18_+_11751470	1.499	NM_001142339 NM_002071	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr6_-_27782517	1.491	NM_021066	HIST1H2AJ	histone cluster 1, H2aj
chr1_+_164528914	1.480		PBX1	pre-B-cell leukemia homeobox 1
chr9_+_80911990	1.462	NM_021154 NM_058179	PSAT1	phosphoserine aminotransferase 1
chr6_-_139613114	1.452	NM_153235	TXLNB	taxilin beta
chr2_-_222436996	1.441	NM_004438	EPHA4	EPH receptor A4
chr1_+_228337414	1.435	NM_020435	GJC2	gap junction protein, gamma 2, 47kDa
chr5_+_140213968	1.422	NM_018910 NM_031852	PCDHA7	protocadherin alpha 7
chr6_+_43138919	1.412	NM_003131	SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr3_-_50649110	1.402	NM_013324 NM_145071	CISH	cytokine inducible SH2-containing protein
chr6_+_30688144	1.397	NM_178014	TUBB	tubulin, beta class I
chr6_+_27114860	1.397	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr5_-_64777703	1.383	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr7_+_96635289	1.380	NM_005222	DLX6	distal-less homeobox 6
chr9_-_131940481	1.371		IER5L	immediate early response 5-like
chr3_-_99594915	1.370	NM_014890	FILIP1L	filamin A interacting protein 1-like
chrX_+_68048792	1.369	NM_004429	EFNB1	ephrin-B1
chr7_+_80267922	1.366		CD36	CD36 molecule (thrombospondin receptor)
chr10_+_90484300	1.363	NM_001080518	LIPK	lipase, family member K
chr9_-_131940538	1.361	NM_203434	IER5L	immediate early response 5-like
chr1_+_161228516	1.356	NM_001102566	PCP4L1	Purkinje cell protein 4 like 1
chr5_-_111093251	1.350	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr11_-_568419	1.348		MIR210HG	MIR210 host gene (non-protein coding)
chr6_+_43139190	1.338		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr6_+_30688085	1.321		TUBB	tubulin, beta class I
chr22_+_38035694	1.321		SH3BP1	SH3-domain binding protein 1
chr1_-_2461683	1.315	NM_001010926	HES5	hairy and enhancer of split 5 (Drosophila)
chr15_-_48470453	1.315	NM_016132	MYEF2	myelin expression factor 2
chr15_+_98503907	1.301	NM_183376	ARRDC4	arrestin domain containing 4
chr11_+_71846755	1.286	NM_000804	FOLR3	folate receptor 3 (gamma)
chr16_-_79634610	1.284	NM_001031804 NM_005360	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
chr22_+_38035718	1.280		SH3BP1	SH3-domain binding protein 1
chr6_-_31689455	1.280	NM_025261	LY6G6C	lymphocyte antigen 6 complex, locus G6C
chr11_+_12132063	1.257	NM_014632	MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2
chr14_+_85996512	1.255		FLRT2	fibronectin leucine rich transmembrane protein 2
chr7_+_5632453	1.226		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr7_+_80267972	1.222		CD36	CD36 molecule (thrombospondin receptor)
chr7_+_5632435	1.219	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr10_+_71812536	1.207		H2AFY2	H2A histone family, member Y2
chr5_+_140557370	1.203	NM_019120	PCDHB8	protocadherin beta 8
chr14_-_23388380	1.203	NM_001077351 NM_001077352 NM_018107	RBM23	RNA binding motif protein 23
chr15_-_48470319	1.193		MYEF2	myelin expression factor 2
chr16_+_8768403	1.192	NM_020686	ABAT	4-aminobutyrate aminotransferase
chr19_+_55888203	1.186	NM_139172	TMEM190	transmembrane protein 190
chr1_-_112531669	1.181	NM_004980 NM_172198	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3
chr1_+_203096835	1.177	NM_000674 NM_001048230	ADORA1	adenosine A1 receptor
chr10_+_71812356	1.166	NM_018649	H2AFY2	H2A histone family, member Y2
chr15_+_98503938	1.164		ARRDC4	arrestin domain containing 4
chr6_+_43139201	1.158		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr14_-_23388359	1.148		RBM23	RNA binding motif protein 23
chr1_-_16161279	1.142
chr3_+_193853930	1.140	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr6_+_105404922	1.139	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr9_-_140196702	1.119	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr17_+_74864427	1.111	NM_001199172 NM_144677	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr2_-_134326030	1.097	NM_207363 NM_207481	NCKAP5	NCK-associated protein 5
chr1_+_145727712	1.095		PDZK1	PDZ domain containing 1
chr10_-_103874661	1.093	NM_003893	LDB1	LIM domain binding 1
chr12_-_81763127	1.093	NM_001220479 NM_001220480	PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr1_-_223537400	1.091	NM_001037175 NM_017982	SUSD4	sushi domain containing 4
chr1_-_204463512	1.089		PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide
chr1_-_32801606	1.082	NM_023009	MARCKSL1	MARCKS-like 1
chr5_+_50679239	1.080		ISL1	ISL LIM homeobox 1
chr17_-_39684499	1.078		KRT19	keratin 19
chr3_-_59035737	1.074		C3orf67	chromosome 3 open reading frame 67
chr7_+_121513158	1.071	NM_001206838 NM_001206839 NM_002851	PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr5_-_95297424	1.044		ELL2	elongation factor, RNA polymerase II, 2
chr5_+_140777603	1.031	NM_018925 NM_032099	PCDHGB5	protocadherin gamma subfamily B, 5
chr2_-_220083658	1.028		ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr21_-_32931289	1.023	NM_003253	TIAM1	T-cell lymphoma invasion and metastasis 1
chr15_+_82647307	1.021		UBE2Q2P2	ubiquitin-conjugating enzyme E2Q family member 2 pseudogene 2
chr10_+_12391728	1.004		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr12_-_89746244	1.004	NM_001946 NM_022652	DUSP6	dual specificity phosphatase 6
chr1_+_180897572	0.999
chr1_-_68697997	0.998	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr8_-_121824287	0.997	NM_021021	SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr4_-_186732047	0.996	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr14_-_71275732	0.995	NM_033141	MAP3K9	mitogen-activated protein kinase kinase kinase 9
chr5_-_146460991	0.988	NM_181677 NM_181678	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta
chr20_+_44746889	0.987	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr14_+_85996454	0.986	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr2_+_37571752	0.981	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr22_+_33197678	0.981		TIMP3	TIMP metallopeptidase inhibitor 3
chr1_-_43424536	0.977		SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr16_-_3068161	0.976	NM_021195	CLDN6	claudin 6
chr19_+_1249882	0.969		MIDN	midnolin
chr3_+_25469833	0.967	NM_000965	RARB	retinoic acid receptor, beta
chr2_-_130956011	0.959	NM_207312	TUBA3E	tubulin, alpha 3e
chr3_-_27764197	0.958		EOMES	eomesodermin
chr1_+_45805877	0.956		TOE1	target of EGR1, member 1 (nuclear)
chr7_-_99774821	0.956	NM_152742	GPC2	glypican 2
chr2_-_217560247	0.955	NM_000599	IGFBP5	insulin-like growth factor binding protein 5
chr2_+_102314162	0.954	NM_001242560 NM_004834 NM_145686 NM_001242559 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr19_+_1491000	0.951	NM_138393	REEP6	receptor accessory protein 6
chr2_-_161056762	0.948		ITGB6	integrin, beta 6
chr15_+_80696569	0.943	NM_014862	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr17_-_41623652	0.936	NM_001079675	ETV4	ets variant 4
chr2_-_43453724	0.934		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr2_+_202047620	0.931	NM_001206524 NM_001206542 NM_001230 NM_032974 NM_032976 NM_032977	CASP10	caspase 10, apoptosis-related cysteine peptidase
chr20_-_30795346	0.927	NM_002657	PLAGL2	pleiomorphic adenoma gene-like 2
chr7_-_117513466	0.923		CTTNBP2	cortactin binding protein 2
chr1_-_38512446	0.912	NM_002699	POU3F1	POU class 3 homeobox 1
chr1_-_205290756	0.904	NM_030952	NUAK2	NUAK family, SNF1-like kinase, 2
chrX_+_67913479	0.903	NM_001142504	STARD8	StAR-related lipid transfer (START) domain containing 8
chrX_-_19817907	0.901	NM_001024666	SH3KBP1	SH3-domain kinase binding protein 1
chr6_+_17282931	0.899	NM_153020	RBM24	RNA binding motif protein 24
chr1_+_45805669	0.898		TOE1	target of EGR1, member 1 (nuclear)
chr3_+_39509069	0.892	NM_182935	MOBP	myelin-associated oligodendrocyte basic protein
chrX_+_105937067	0.892	NM_024539	RNF128	ring finger protein 128
chr1_+_45805783	0.886		TOE1	target of EGR1, member 1 (nuclear)
chr17_+_18128868	0.882	NM_004140	LLGL1	lethal giant larvae homolog 1 (Drosophila)
chrX_-_47931000	0.881	NM_001190255	ZNF630	zinc finger protein 630
chr8_-_110693233	0.881	NM_001099745 NM_001099746	SYBU	syntabulin (syntaxin-interacting)
chr11_-_128457452	0.877	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr1_-_152297678	0.873	NM_002016	FLG	filaggrin
chr15_+_89164522	0.868	NM_022767	AEN	apoptosis enhancing nuclease
chr12_-_11422640	0.867	NM_006249	PRB3	proline-rich protein BstNI subfamily 3
chr19_-_18717467	0.861		CRLF1	cytokine receptor-like factor 1
chr17_-_74722614	0.859		JMJD6	jumonji domain containing 6
chr4_-_170077807	0.858		SH3RF1	SH3 domain containing ring finger 1
chr6_+_83072922	0.856	NM_006670	TPBG	trophoblast glycoprotein
chr10_+_12391708	0.854		CAMK1D	calcium/calmodulin-dependent protein kinase ID
chr11_+_67007484	0.853		LOC100131150	uncharacterized LOC100131150

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.78	1.46e-03	GO:0007399	nervous system development
1.86	8.07e-03	GO:0032502	developmental process
1.91	1.15e-02	GO:0007275	multicellular organismal development
3.23	1.16e-02	GO:0048699	generation of neurons
2.03	1.31e-02	GO:0048731	system development
1.93	2.20e-02	GO:0048856	anatomical structure development
3.05	2.45e-02	GO:0022008	neurogenesis
3.23	3.84e-02	GO:0007155	cell adhesion
3.23	3.84e-02	GO:0022610	biological adhesion
2.10	4.59e-02	GO:0042221	response to chemical stimulus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
33.90	1.33e-02	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
31.48	1.69e-02	GO:0033549	MAP kinase phosphatase activity